The Center for Precision Synthesis, Institute

for Advanced Studies, Wuhan University

Recent Publications

44. Zhengtian Ding, Yiming Wang, Wenfeng Liu, Yate Chen and Wangqing Kong*.  Diastereo- and Enantioselective Construction of Spirocycles by Nickel-Catalyzed Cascade Borrowing Hydrogen Cyclization. J. Am. Chem. Soc.,(in press) DOI: 10.1021/jacs.0c10055



43. Sheng Xu, Herong Chen, Zhijun Zhou and Wangqing Kong*.  Three-Component Alkene Difunctionalization via Direct and Selective Activation of Aliphatic C-H Bonds. Angew. Chem. Int. Ed. (in press) DOI: 10.1002/anie.202014632



42. Yate Chen, Zhengtian Ding, Yiming Wang, Wenfeng Liu and Wangqing Kong*. Synthesis of Indanones and Spiroindanones by Diastereoselective Annulation Based on a Hydrogen Autotransfer Strategy. Angew. Chem. Int. Ed., (in press) DOI: 10.1002/anie.202013792.



41. Wenfeng Liu and Wangqing Kong*. Ni-Catalyzed stereoselective difunctionalization of alkynes. Org. Chem. Front., 2020, 7: 3941-3955. (Invited Review)





40. Baihang Ju and Wangqing Kong*. Recent Progress in the Consecutive Double Heck Reaction. Asian J. Org. Chem., 2020, 9: 1154 –1161. (Invited Review)




39. Zhijun Zhou, Wenfeng Liu and Wangqing Kong*. Ni-Catalyzed Reductive Antiarylative Cyclization of Alkynones. Org. Lett., 2020, 22: 69826987.



38. Zhijun Zhou, Jiachang Chen, Herong Chen and Wangqing Kong*. Stereoselective synthesis of pentasubstituted 1,3-dienes via Ni-catalyzed reductive coupling of unsymmetrical internal alkynes. Chem. Sci., 2020, 11: 10204-10211.



37. Zhijun Zhou, Sheng Xu, Jing Zhang* and Wangqing Kong*. Nickel-catalyzed enantioselective electroreductive cross-couplings. Org. Chem. Front., 2020, 7: 3262-3265.



36. Yuanyuan Ping and Wangqing Kong*. Ni-Catalyzed Reductive Difunctionalization of Alkenes. Synthesis, 2020, 52: 979–992. (Invited Review)




35. Jiachang Chen, Yiming Wang, Zhengtian Ding, and Wangqing Kong*. Synthesis of bridged tricyclo[5.2.1.01,5]decanes via nickel-catalyzed asymmetric domino cyclization of enynones. Nat. Commun., 2020, 11, 1882.



34. Baihang Ju, Shigui Chen, Wangqing Kong. Pd-Catalyzed Enantioselective Double Heck Reaction. Organic Letters 2019 21 (23), 9343-9347




33. Baihang Ju, Shigui Chen, Wangqing Kong. Enantioselective palladium-catalyzed diarylation of unactivated alkenes. Chem. Commun. 2019, 55, 14311-14314



32.Teng Ma, Yate Chen, Yuxiu Li, Yuanyuan Ping and Wangqing Kong*.Nickel-Catalyzed Enantioselective Reductive Aryl Fluoroalkenylation of Alkenes. ACS Catal., 2019, 9, 9127-9133



31. Sheng Xu, Kuai Wang and Wangqing Kong*. Ni-Catalyzed Reductive Arylacylation of Alkenes toward Carbonyl-Containing Oxindoles. Org. Lett., 2019, 21, 7498-7503




30. Yuxiu Li, Zhengtian Ding, Aiwen Lei* and Wangqing Kong*. Ni-Catalyzed enantioselective reductive aryl-alkenylation of alkenes: application to the synthesis of (+)-physovenine and (+)-physostigmine. Org. Chem. Front., 2019, 6, 3305-3309




29. Yuanyuan Ping, Kuai Wang, Qi Pan, Zhengtian Ding, Zhijun Zhou, Ya Guo, and Wangqing Kong*. Ni-Catalyzed Regio- and Enantioselective Domino Reductive Cyclization: One-Pot Synthesis of 2,3-Fused Cyclopentannulated Indolines. ACS Catal. 2019, 9, 7335−7342.





28. Kuai Wang and Wangqing Kong*. Enantioselective Reductive Diarylation of Alkenes by Ni-Catalyzed Domino Heck Cyclization/Cross Coupling. Synlett 2019, 23,1103-1107. (Synpact article: invited review highlighting work in pub. 27)



27. Kuai Wang, Zhengtian Ding, Zhijun Zhou, and Wangqing Kong*. Ni-Catalyzed Enantioselective Reductive Diarylation of Activated Alkenes by Domino Cyclization/Cross-Coupling. J. Am. Chem. Soc., 2018, 140, 12364-12368.





26. Yuanyuan Ping, Yuxiu Li, Jieping Zhu*, Wangqing Kong*. Construction of Quaternary Stereocenters by Palladium‐Catalyzed Carbopalladation‐Initiated Cascade Reactions.Angew. Chem. Int. Ed. 2019, 58: 1562-1573.



25. Yuxiu Li, Kuai Wang, Yuanyuan Ping, Yifan Wang, and Wangqing Kong*. Nickel-Catalyzed Domino Heck Cyclization/Suzuki Coupling for the Synthesis of 3,3-Disubstituted Oxindoles. Org. Lett. 2018, 20, 921−924 (Highlighted by Synfacts, 2018, 14(4), 410)




24. Kuai Wang, Wangqing Kong*. Recent Advances in Transition Metal Catalyzed Asymmetric Radical Reactions. Chin. J. Chem. 2018, 36, 247-256. (Cover Story)